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홍차넷
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티타임
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- 다양한 주제에 대해 자유롭게 글을 작성하는 게시판입니다.
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전체기타일상/생각꿀팁/강좌방송/연예도서/문학영화의료/건강문화/예술경제생활체육과학/기술철학/종교정치요리/음식역사여행육아/가정IT/컴퓨터음악창작게임스포츠사회오프모임
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| Date |
Warning: Use of undefined constant reg_date - assumed 'reg_date' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view.php on line 53 17/02/24 10:54:14 Warning: Use of undefined constant mod_date - assumed 'mod_date' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view.php on line 56 |
| Name | 모모스 |
| Subject | 김정남 암살에 사용된 것으로 유력한 신경가스 - VX가스 |
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VX 가스  VX가스는 1991년 유엔에서 대량살상무기로 분류한 무색무취의 독가스입니다. 아세틸콜린 (Acetylcholine)  아세틸콜린은 주로 부교감신경에 작용하는 신경전달물질로 아세틸콜린이 분비되면 혈압강하, 심박동수감소, 동공축소, 소화기능활성화, 근골격근의 흥분 등의 작용이 나타납니다.  신경말단에서 분비된 아세틸콜린은 Acetylcholinesterase에 의해 가수분해되어 작용이 조절되는데 신경가스인 VX는 Acetylcholinesterase를 저해하여 Acetylcholine의 작용을 조절하지 못하고 보통 심장마비로 사망하고 맙니다. LD50는 피부접촉이나 호흡기나 점막을 통한 흡수 등에 따라 다르나 대략 0.2~2 mg/kg 정도 수준으로 10mg 정도면 성인 한명이 사망합니다. LD50은 지난 번 글 (보톡스) 에서 설명한 적이 있습니다. " Lethal Dose 50 (LD50)  여러가지 독성물질의 독성정도를 비교하는 지표로 LD50 이란 것을 사용합니다. 주로 mouse를 사용하는데 독소를 여러가지 용량(Dose) 별로 투여한 후 죽은 mouse의 수를 그래프로 그리면 sigmoidal curve를 나타납니다. 이는 지수함수를 따른다고 알려져있는데 전통적으로 주로 역수를 취한 후 ln를 씌우면 1차함수 직선으로 나타나고 이를 least square method 로 기울기와 절편을 구해서 역으로 50%가 죽는 Dose를 구했습니다. ln를 씌여서 계산한 값이라서 오차가 많으므로 요즘은 Nonliner regression 해주는 프로그램으로 사용하여 LD50 구합니다. 잘하시는 분들은 Weight 도 주죠. 아무튼 독성물질의 독성 수준을 비교하는 대표적인 지표입니다. mouse에 정맥투여 후 현재 알려진 LD50 (Mice LD50 in intravenus) Botulinum toxin 0.01 µg/kg 황금독화살개구리의 바트라코톡신 (Batrachotoxin) 2 µg/kg 암살자 리신 (Ricin) 5 µg/kg 복어독 (Tetrodotoxin) 10 µg/kg " 영화 "더록"에 테러용으로 사용된 독가스가 바로 VX가스입니다.  해독제로는 아세틸콜린의 작용을 억제하는 약물인 anticholinergic drug 를 사용하는데 아트로핀 (Atropine)이 대표적입니다. 다만 긴급할 때만 쓰는 매우 위험한 약물 (현재는 주로 교감신경을 자극하는 약물들을 더 선호합니다.) 로 조금만 용량을 많게나 적게 투여하면 목숨을 잃을 수도 있습니다.  영화 "더록" 에서 리콜라스 케이지가 VX에 노출된 후 아트로핀 (Atropine), 2-PAM (Pralidoxime) 또는 교감신경을 자극하는 anticholinergic drug로 추정되는 주사를 자신의 심장에 직접 주사합니다. 심장에 직접 주사할 때 매우 매우 주의해야하는데 정확한 위치에 해야하고 저렇게 큰바늘로 주사하면 아마 심장조직의 손상으로 죽을 수도... 그냥 엉덩이나 허벅지 등에 주사하면 될 듯... 김정남은 VX에 노출된 후 anticholinergic drug 을 신중하게 용량을 조절하여 주사를 맞았다면 살았을 수도 있겠네요. 하지만 테러당시 어떤 독극물인지 알 수가 없었으니 골든타임을 놓쳤겠죠. 사용한 양에 따라 다르겠지만 김정남 암살에 VX가 사용되었다면 말레이시아 쿠알라룸푸르 공항은 테러 후 바로 폐쇄했어야.... 북한은 참 막나가는 국가에요. 사람들이 많은 타국의 공항에서 대량살상무기인 VX가스를 사용을 하다니.. Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view.php on line 133 Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view.php on line 146 Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view.php on line 161 6
이 게시판에 등록된 모모스님의 최근 게시물
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71560 class="iamcmt" style="display:none;"> Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 66
71560 class='vcm '>
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Warning: Use of undefined constant ismember - assumed 'ismember' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 117
Warning: Use of undefined constant ismember - assumed 'ismember' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 118
Warning: Use of undefined constant ismember - assumed 'ismember' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 119
Warning: Use of undefined constant ismember - assumed 'ismember' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 120
Warning: Use of undefined constant ismember - assumed 'ismember' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 121
71560'> 조홍
Warning: Use of undefined constant mod_date - assumed 'mod_date' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 133
Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 140
Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 140
Warning: Use of undefined constant reg_date - assumed 'reg_date' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 142
17/02/24 10:59
71560>삭제 주소복사
Warning: Use of undefined constant level - assumed 'level' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 150
티모 평q평 천둥 콰광이 아니었군요
그런데 저런걸 어떻게 잘 공항 검열 통과시켜서 썼을까요?
Warning: Use of undefined constant level - assumed 'level' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 158
Warning: Use of undefined constant password - assumed 'password' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 166
Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 171
Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 172
Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 172
Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 173
Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 173
Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 173
그런데 저런걸 어떻게 잘 공항 검열 통과시켜서 썼을까요?
Warning: Use of undefined constant level - assumed 'level' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 158
Warning: Use of undefined constant password - assumed 'password' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 166
Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 171
Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 172
Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 172
Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 173
Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 173
Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 173
71560>
71560>
