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홍차넷
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티타임
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- 다양한 주제에 대해 자유롭게 글을 작성하는 게시판입니다.
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전체기타일상/생각꿀팁/강좌방송/연예도서/문학영화의료/건강문화/예술경제생활체육과학/기술철학/종교정치요리/음식역사여행육아/가정IT/컴퓨터음악창작게임스포츠사회오프모임
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| Date |
Warning: Use of undefined constant reg_date - assumed 'reg_date' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view.php on line 53 15/09/16 18:00:30 Warning: Use of undefined constant mod_date - assumed 'mod_date' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view.php on line 56 |
| Name | Beer Inside |
| File #1 | impricision_medicine.tif (912.4 KB), Download : 11 |
| Subject | 몇명의 환자에게 같은 약을 주면 한명이 치료될까? |
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Needed Number to Treat라는 개념이 있습니다. 다른 말로는 N of 1 trial이라고도 합니다. (뭔 소리인지 정확하게 알고 싶다는 분은 아래의 링크를... http://www.healthknowledge.org.uk/public-health-textbook/research-methods/1a-epidemiology/nnts 하지만 읽다가 구토가 발생할 수도 있으니... ) 동일한 약을 몇명에게 주면 한 명에게 효과가 있을까라는 의문에서 시작된 것 같은 통계 지표입니다. 예를 들면 진통제를 먹고 통증이 30%이상 줄어들면 이 진통제는 통증 감소에 효과가 있다고 할 때, 몇명에게 동일한 약을 먹여야 30% 이상의 통증감소 효과가 있는 환자를 한명 만날 수 있는가 하는 것이지요. 의학논문에서 가끔씩 사용하는 통계인데, 리뷰 논문이나 논문의 내용이 특별한 것이 없을 때 사용하기도 합니다. 최근에 미국에서 판매량이 증가하고 있는 순서대로 10개를 정해서 이 NNT를 조사했더니 놀라운 결과가 나왔습니다.  판매량이 증가하는 약물 Top 10 약물이라는 것은, 최근에 개발한, 의사들이 선호하는, 고가의 약물이라는 뜻을 어느정도 가지고 있는데, 효과가 좋은 약은 4명에게 투약을 하면 한명이 치료되고, 효과가 나쁜 약은 25명을 투약하면 한병이 치료된다는 것이였습니다. 물론 질병이라는 것이 약만 먹는다고 치료된다면 커피마시지마라, 생활개선해라 같은 잔소리를 하는 의사가 대폭 줄어들겠지만, 비교적 최근에 개발된 고가의 약들의 효과가 기대치 보다 못 미친다고 하니 놀라운 일이였지요. 그래서 이런 방식의 치료를 부정확한 의학이라고 규정하고 새로운 방식의 정확한 의학( Precision Medicine)을 주창하게 됩니다. 실제로 정확한 의학은 새로운 개념은 아닙니다. 과거 혈액형을 모르던 시절 출혈을 하는 환자에게 수혈을 했을 때 어떤 환자는 수혈 적합한 혈액을 수혈받아서 살고, 어떤 환자는 부적합한 혈액을 수혈받아서 죽던 시절이 있었습니다. 이후 교차시험(Cross Matching) 및 혈액형의 연구의 결과에 따라서 환자에게 적합한 수혈을 해 줄 수 있었지요. 그래서 수혈처럼 어떤 환자에게 어떤 약이 적합한지를 연구하는 것이 Precision Medicine이고, 이 적합성을 알아내는데 유전자가 많은 역할을 할 것이라고 생각되어서, 오바마 정부는 대대적인 투자를 결정했습니다. 지금은 항암제 투여시에 환자의 유전자형에 따라서 항암제를 어떻게 투여할지를 고민하고 있는데, 10년 정도 지나면 어느 정도 발달해 있을지 궁금합니다. Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view.php on line 133 Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view.php on line 146 Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view.php on line 161 0 이 게시판에 등록된 Beer Inside님의 최근 게시물
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15057 class="iamcmt" style="display:none;"> Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 66
15057 class='vcm '>
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15057'> Beer Inside
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15/09/16 18:26
15057>삭제 주소복사
Warning: Use of undefined constant level - assumed 'level' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 150
이미지 삽입이 어렵군요.
잘 보이지 않는 이미지는
http://imgur.com/jRKlmBx
입니다.
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Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 172
Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 173
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Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 173
잘 보이지 않는 이미지는
http://imgur.com/jRKlmBx
입니다.
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Warning: Use of undefined constant password - assumed 'password' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 166
Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 171
Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 172
Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 172
Warning: Use of undefined constant no - assumed 'no' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 173
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Warning: Use of undefined constant vote - assumed 'vote' (this will throw an Error in a future version of PHP) in /home/redtea/html/a_skin/bbsd/view_comment.php on line 173
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